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目的运用弥散张量成像(DTI)定量研究不同血压水平的变化对无症状中年人脑白质部位的各向异性特点。方法选择临床无症状中年人60名,按血压水平分为3组,均行DTI检查。分析其表面弥散系数(ADC)图及各向异性分数(FA)图的特点,并对各组相同部位脑白质进行ADC值及FA值行定量分析,通过统计学分析得出其弥散系数和各向异性特点。结果 DTI可清晰显示脑内白质的走行及方向。不同血压水平对相同年龄组相同解剖部位脑白质ADC值及FA值的差异有统计学意义。FA值能准确定量分析无症状正常人脑白质部位的各向异性特点。结论血压的升高,可造成脑血管的缓慢损伤。即使在无症状中年人中,微小的血管性脑损伤也可在生活中隐匿性发生,并产生明显的影像学效应。研究强调了早期控制血压达标的重要性。
Objective To quantitatively study the anisotropy of white matter in asymptomatic middle-aged people with different blood pressure levels by diffusion tensor imaging (DTI). Methods Sixty middle-aged asymptomatic asymptomatic patients were selected and divided into three groups according to their blood pressure. All patients underwent DTI. The surface diffusion coefficient (ADC) and the anisotropy fraction (FA) were analyzed. The ADC values and FA values of white matter in the same group in each group were quantitatively analyzed. The diffusion coefficient The opposite sex characteristics. Results DTI can clearly show the white matter in the brain travel and direction. Different blood pressure levels in the same age group at the same anatomical location of white matter ADC values and FA values were significantly different. FA value can accurately quantify the anisotropy of asymptomatic normal white matter. Conclusion The increase of blood pressure can cause the slow damage of cerebrovascular. Even in asymptomatic middle-aged people, tiny vascular brain injury can occur occultly in life and produce significant imaging effects. The study highlights the importance of early control of blood pressure compliance.