患者、男、44岁,以发热伴全身痛、腹泻6d于1988年7月8日入院。起病初发热、全身疼痛不适,腰痛、腹痛,腹泻为稀水便,5～6次/d,伴有恶心,不思饮食,按“菌痢”给“痢特灵”、“庆大霉素”等治疗无效,热不退经服“APC”汗出但病情更趋加重,转来我院.入院时T37.2C,P84次/min,BP17.4kPa,精神差,意识清.三红征(+)。软腭及皮肤可见针帽大小多个出血点。眼球结膜充血、无水肿。心肺(-)。血管脆性试验(+)。腹部平软,脐周有轻度压痛,肝脾未触及,肠鸣音活跃。双肾区叩痛明显。脊柱、四肢及 Patients, male, 44 years old, with fever and generalized pain, diarrhea 6d on July 8, 1988 admitted. Early onset of fever, body aches and discomfort, back pain, abdominal pain, diarrhea, watery, 5 to 6 times / d, with nausea, do not think diet, according to “bacillary dysentery” to “furazolidone” Vegetarian “and other treatment is ineffective, refreshed by the service” APC "sweating but the condition worsened, transferred to our hospital admission T37.2C, P84 times / min, BP17.4kPa, poor spirits, clear consciousness. Sign (+). Soft palate and the size of the needle cap can see multiple bleeding points. Eye conjunctival hyperemia, no edema. Cardiopulmonary (-). Vascular fragility test (+). Abdomen soft, umbilical mild tenderness, liver and spleen not touched, bowel sounds active. Perineal area percussion pain significantly. Spine, limbs and