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目的探讨影响面神经炎合并2型糖尿病(DM)患者预后恢复的因素。方法 92例面神经炎患者,根据血糖及糖化血红蛋白(Hb A1c)指标分为面神经炎无DM患者31例(A组),面神经炎合并DM且Hb A1c≤7.0%患者31例(B组);面神经炎合并DM且Hb A1c>7.0%患者30例(C组)。收集患者的临床资料及预后分级进行统计学分析。结果 B组与C组均较A组有较高的空腹血糖(FPG)和甘油三酯(TG)水平,差异具有统计学意义(P<0.05);C组Hb A1c、LDL-C、开始恢复时间和预后级别均高于A组和B组,差异具有统计学意义(P<0.05)。面神经瘫痪开始恢复时间的影响因素是FPG和TG(B=22.157,β1=2.384,β2=1.646,P<0.001);预后级别的影响因素是Hb A1c和LDL-C(B=0.246,β1=0.114,β2=0.107,P=0.002<0.01)。结论血糖控制不佳、高脂血症的面神经炎患者病情容易迁延不愈,预后较差。
Objective To investigate the factors that affect the prognosis recovery of patients with facial neuritis and type 2 diabetes mellitus (DM). Methods Thirty-two patients with facial neuritis were divided into 31 patients with facial neuritis without DM (group A), 31 patients with facial neuritis complicated with DM and Hb A1c ≤ 7.0% (group B) according to the indexes of blood glucose and Hb A1c; Thirty patients with inflammation with DM and Hb A1c> 7.0% (Group C). The clinical data and prognosis grade were collected for statistical analysis. Results The fasting blood glucose (FPG) and triglyceride (TG) levels in group B and group C were significantly higher than those in group A (P <0.05). The levels of Hb A1c and LDL-C in group C began to recover The time and the level of prognosis were higher than those in group A and group B, the difference was statistically significant (P <0.05). The factors affecting the recovery time of facial nerve paralysis were FPG and TG (B = 22.157, β1 = 2.384, β2 = 1.646, P <0.001). The influencing factors of prognosis were Hb A1c and LDL-C , β2 = 0.107, P = 0.002 <0.01). Conclusion Poor blood glucose control, hyperlipidemia in patients with facial neuritis easily delayed healing, the prognosis is poor.