多发性骨髓瘤是老年人较常见的恶性血液系统肿瘤,除异基因造血干细胞移植外,尚无根治愈疗法。近年来多种新型药物逐步应用于临床并取得令人振奋的疗效。沙利度胺、雷利度胺、硼替佐米、三氧化二砷已作为MM的一线或二线治疗药物应用于临床。 Multiple myeloma is a common malignant hematological malignancy in the elderly. In addition to allogeneic hematopoietic stem cell transplantation, there is no radical cure. In recent years, a variety of new drugs gradually applied to clinical and achieved exciting results. Thalidomide, lenalidomide, bortezomib, arsenic trioxide has been used as a first-line or second-line treatment of MM in clinical.