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最近的研究发现,慢性丙型肝炎患者血清中肿瘤坏死因子α(TNF-α)水平升高,本文作者的研究目的是探讨慢性丙型肝炎患者对IFN-α治疗的反应性与TNF-α产生之间的关系。 研究对象分为3组:第1组为47例慢性丙型肝炎患者和17例正常对照,检测血清TNF-α水平。其中16例未经治疗,31例进行了不同剂量的全程IFN-α治疗(3MU/天×2个月和3MU,3次/周×8～12个月),第2组为61例慢性丙型肝炎患者的71份外周血单
Recent studies have found that serum TNF-α levels are elevated in patients with chronic hepatitis C, and the authors’ study aimed to investigate the association of TNF-α production with IFN-α-responsiveness and chronic hepatitis C The relationship between. The subjects were divided into three groups: group 1, 47 patients with chronic hepatitis C and 17 normal controls, serum TNF-α levels were measured. Thirty-six patients were treated with different doses of IFN-α (3MU / day × 2 months and 3MU, 3 times / week × 8-12 months), and the second group was 61 chronic C 71 peripheral blood monocytes in patients with hepatitis