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目的探讨生长迟缓儿血铅水平现状及其相关的影响因素。方法采用电感耦合高频等离子体原子发射光谱法,对269例身高、体重发育落后儿进行血铅含量的测定,并对小儿生长发育状况及家庭、生活环境等相关因素进行问卷调查。结果①在269例生长迟缓儿中,血铅最高值为29μg/dl,最低值为5μg/dl,几何均值为13μg/dl,≥10μg/dl者156例,占57.8%;②血铅水平与身高-sd为正相关,r=0.0878,P<0.05;与体重-sd相关性不显著,r=0.0533,P>0.1;③生长迟缓儿与正常儿血铅水平差异有显著性,U=22142.5,P<0.01。④线性回归分析显示血铅水平与生活环境因素(父母职业、交通工具、饮用牛奶、手-口习惯、居住地理)有显著性差异,P<0.01。结论铅中毒可导致儿童身高增长减慢,生长迟缓儿血铅水平高于生长发育正常儿,血铅水平与生活环境因素有关。
Objective To investigate the status of blood lead levels and its related influencing factors in children with growth retardation. Methods Inductively Coupled Plasma-Atomic Emission Spectrometry (ICP-AES) was used to determine the blood lead levels in 269 children with obese height and weight. Children’s growth and development, family and living environment were investigated by questionnaire. Results ① In 269 cases of growth retardation, the highest blood lead level was 29μg / dl, the lowest was 5μg / dl, the geometric mean was 13μg / dl, and 156 cases were ≥10μg / dl, accounting for 57.8%. ② The levels of blood lead Height-sd was positively correlated, r = 0.0878, P <0.05; and body weight-sd correlation was not significant, r = 0.0533, P> 0.1; ③ growth retardation and normal children’s blood lead levels were significantly different, U = 22142.5 , P <0.01. (4) The linear regression analysis showed that there was a significant difference between blood lead levels and living environment factors (parental occupation, transportation, drinking milk, hand-mouth habits, living geography), P <0.01. Conclusion Lead poisoning can lead to the slow growth of children’s height, blood lead levels in children with delayed growth is higher than normal growth and development, blood lead levels and living environment factors.