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评价沪 191麻疹疫苗近期和远期的流行病学效果。以 1991年 10月在荆州区川店镇建立麻疹疫苗免疫效果观察点 ,5 0 3名麻疹疫苗初免儿童 (其中 10 1名于 1年后进行加强免疫 )作为观察对象 ,1992～1999年连续对观察点所有发热、出疹病人 (RFIs)进行监测 ,并采血作麻疹和风疹血清学鉴别诊断。结果 1992年和 1993年各发生 1例麻疹 ,1999年发生一起麻疹和风疹混合暴发流行 ,查 15 0例病人中的 91例病人血 ,麻疹血清学阳性 5 6例 ,其中 2 6例风疹 Ig M同时阳性。所有 RFIs病例中 ,仅 1例为麻疹疫苗观察对象 ,该儿童麻疹疫苗初免未成功 ,属原发性免疫失败病例。流行后期 ,查 19名麻苗观察对象麻疹 Ig G,隐性感染率为94.74% (18/19)。结果表明 ,沪 191麻疹疫苗近期和远期的流行病学效果是满意的
Evaluation of the Shanghai 191 measles vaccine, the long-term and long-term epidemiological effects. In October 1991, an immunization impact point of measles vaccine was established in Chuandian Town, Jingzhou District. Of the 530 measles immunization children (among whom 101 were immunized one year after immunization) as the observation target, from 1992 to 1999, continuous All fever and rash patients (RFIs) were monitored at the observation point and blood was collected for differential diagnosis of measles and rubella serology. Results One case of measles occurred in 1992 and one case in 1993. A mixed outbreak of measles and rubella occurred in 1999. The blood of 91 patients was investigated in 151 patients and the positive serology of measles was 56. Among them, 26 cases of rubella Ig M Positive at the same time. Of all RFIs cases, only one case was observed for measles vaccine, and the initial immunization failed for this measles vaccine in children. Popular late, check the 19 measles vaccine measles Ig G, the latent infection rate was 94.74% (18/19). The results showed that the epidemiological effect of Shanghai 191 measles vaccine in the near and long-term was satisfactory