酸性成纤维细胞生长因子(aFGF)是一种新的神经营养因子。它主要存在于动物的脑组织中,参与中枢神经系统的生长发育及神经损伤的修复与再生。目前有关aFGF在神经系统中作用的研究已有较多报道,但是对aFGP究竟是由神经组织中哪些细胞产生还不十分清楚。其主要原因是aFGF基因为单拷贝,其mRNA的含量在神经组织中很低,且又不稳定,很难直接从基因转录水平上证实神经组织中哪些细胞表达aFGF,特别是从体 Acid fibroblast growth factor (aFGF) is a new neurotrophic factor. It is mainly present in the brain tissue of animals and is involved in the growth and development of the central nervous system and the repair and regeneration of nerve damage. At present, there are more reports on the role of aFGF in the nervous system, but it is not yet clear which aFGP is produced in the nerve tissue. The main reason is aFGF gene is a single copy, the mRNA content in nerve tissue is very low, and unstable, it is difficult to directly from the gene transcription level to confirm which cells in nerve tissue express aFGF, especially from the body