早在1962年,Luft等人从临床、生化、形态三个方面对一位非甲状腺性代谢亢进的女性患者进行了认真的研究,随后世界各地陆续有同样的散发病例报道,Price将这一组疾病统称为线粒体肌病(mitochondrial myopalhies)。目前已经证实,线粒体肌病是一组临床和生化的异质性疾病,包括数种不同的综合征:Kearns—Sayre综合征、锯齿样红纤维性 As early as 1962, Luft et al. Conducted a careful study of a woman with non-thyroid hyperthyroidism from clinical, biochemical and morphological aspects. Afterwards, the same case of dissemination was reported all over the world. Price put this group Diseases are collectively known as mitochondrial myopalhies. It has now been demonstrated that mitochondrial myopathy is a group of clinical and biochemical heterogeneity disorders and includes several different syndromes: Kearns-Sayre syndrome, serrated red fibrosis