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我院自1997年以来对经临床诊断的多发性骨髓瘤(MM)15例的尿液进行了检测,发现可在12h尿液中检测出骨髓瘤细胞。现将检测结果报告如下。 1 临床资料 15例中男8例,女7例。年龄34～74(平均56.4)岁。15例均经骨髓涂片、骨髓病理、免疫蛋白电泳确诊。 15例中骨痛9例,贫血14例,发热5例。经CT或磁共振成像证实骨质破坏8例,由B超证实双肾缩小和肾积水各1例。血常规:白细胞(2.7～8.6)×10~9/L,血红蛋白39～135g/L,血沉37～163mm/h。尿常规:6例尿中查到白细胞2～15个,1例红细饱满视野。本-周氏蛋白阳性5例。生化检查:尿素氮3.8～32.0mmol/L,肌酐55～749μmol/L,两项均高于正常值者4例。免疫球蛋白IgG 4.32
In our hospital since 1997, 15 cases of clinically diagnosed multiple myeloma (MM) of urine were detected and found in 12h urine myeloma cells detected. The test results are reported below. A clinical data of 15 cases, 8 males and 7 females. Age 34 ~ 74 (average 56.4) years old. 15 cases were bone marrow smears, bone marrow pathology, immune protein electrophoresis confirmed. 15 cases of bone pain in 9 cases, anemia in 14 cases, fever in 5 cases. CT or magnetic resonance imaging confirmed bone destruction in 8 cases, confirmed by B ultrasound reduction of both kidneys and hydronephrosis in 1 case. Blood: white blood cells (2.7 ~ 8.6) × 10 ~ 9 / L, hemoglobin 39 ~ 135g / L, ESR 37 ~ 163mm / h. Urine routine: 6 cases of leukocytes found in urine 2 to 15, 1 case of red fine full field of vision. Ben-Zhou protein positive in 5 cases. Biochemical tests: urea nitrogen 3.8 ~ 32.0mmol / L, creatinine 55 ~ 749μmol / L, two were higher than the normal in 4 cases. Immunoglobulin IgG 4.32