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对60例头颈部肿瘤放射治疗后患者的血清Cu、Zn、Cu/Zn比值进行了检测。结果显示:放射治疗后复发组血清Cu明显高于正常对照组和放射治疗后无复发组(P<0.001);血清Zn低于正常对照组和放射治疗后无复发组(P<0.01);血清Cu/Zn比值明显高于正常对照组和放射治疗后无复发组(P<0.001)。无复发组的血清Cu、Zn、Cu/Zn比值的检测,特别是血清Cu/Zn比值可作为肿瘤放疗后复发与否的参考指标。
The serum Cu, Zn, and Cu/Zn ratios of 60 patients with head and neck cancer after radiotherapy were examined. The results showed that the serum Cu level in the recurrence group after radiotherapy was significantly higher than that in the normal control group and no recurrence group after radiotherapy (P<0.001); serum zinc was lower than the normal control group and no recurrence group after radiotherapy (P<0. 01); serum Cu/Zn ratio was significantly higher than the normal control group and no recurrence after radiotherapy (P<0.001). The detection of serum Cu, Zn, and Cu/Zn ratios in the relapse-free group, especially the serum Cu/Zn ratio, can serve as a reference for the recurrence of tumors after radiotherapy.