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本文根据国内外文献报导的多态性位点,从中筛选出多态性高,实用 性强,易于扩增分型的 3个 DNA位点(即 APOB、PMCT118、P33.6)。调查了各 位点在广州地区汉族人群中的分布频率、遗传特点及个体识别力,通过计算3位 点两无关个体基因型偶然相同的概率为 2.3 × 10-5,可满足实际检案需要。作 者还对检材处理、实验方法等作了研究。
Based on the polymorphic loci reported in the literature both at home and abroad, we selected three DNA sites (APOB, PMCT118, P33.6) with high polymorphism, strong practicability and easy amplification and typing. The distribution frequency, genetic characteristics and individual identification power of each locus in Han population in Guangzhou area were investigated. By calculating the probability that the two unrelated individual genotypes at the three loci were accidentally identical were 2.3 × 10-5, . The author also examines the material processing, the experiment method and so on has made the research.