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目的:探讨西米替丁治疗过敏性紫癜的疗效。方法:选择48例患者,在一般治疗的基础上,采用西米替丁20mg/kg.d,分2-3次静滴,用药1周余,改口服,维持量为15-20mg/kg.d,分3次,维持用药2-3周;对照组采用一般常规治疗。结果:治疗组的痊愈率为72.9%,有效率为100%,无1例复发;对照组的痊愈率为64.8%,有效率为100%,复发18例(占48.6%)。结论:应用西米替丁治疗过敏性紫癜的疗效显著,可缩短病程,且副作用少。特别是可用于防治过敏性紫癜,明显降低其复发率。
Objective: To investigate the curative effect of cimetidine on allergic purpura. Methods: Forty-eight patients were selected. On the basis of general treatment, cimetidine 20mg / kg.d was administered intravenously 2-3 times for more than one week. The dosage was changed to 15-20mg / kg. d, 3 times, to maintain medication for 2-3 weeks; control group using the conventional treatment. Results: The cure rate of the treatment group was 72.9%, the effective rate was 100%, and none of the patients relapsed. The cure rate of the control group was 64.8%, the effective rate was 100% and the recurrence was 18 (48.6%). Conclusion: The application of cimetidine in the treatment of Henoch-Schonlein Purpura has significant curative effect, shortens the course of the disease and has few side effects. Especially for the prevention and treatment of allergic purpura, significantly reduce the recurrence rate.