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[目的]探讨食管静脉曲张患者内镜下硬化治疗(EVS)后早期再出血的危险因素。[方法]选取2013年5月~2014年10月我院确诊的食管曲张静脉破裂出血经EVS治疗患者行回顾性研究,其中22例EVS治疗后6周内食管静脉曲张再出血患者纳入再出血组,其余68例纳入未出血组,统计分析EVS治疗后早期再出血的危险因素。[结果]2组Child-Pugh分值、凝血酶原时间、白蛋白水平、门静脉直径及血清Na值比较,差异有统计学意义(P=0.037、0.006、0.015、0.026、0.017)。多因素分析表明EVS治疗前Child-Pugh分值、凝血酶原时间、门静脉直径及血清Na值为EVS治疗后早期再出血的独立危险因素。[结论]Child-Pugh分值较高、凝血酶原时间较长、门静脉较宽及血清Na值较高可能预示EVS治疗后早期再出血风险高。
[Objective] To explore the risk factors of early rebleeding after endoscopic sclerosis (EVS) in patients with esophageal varices. [Methods] A retrospective study was conducted on patients with EVS diagnosed with esophageal variceal bleeding in our hospital from May 2013 to October 2014. 22 patients with esophageal variceal bleeding within 6 weeks after EVS treatment were included in the rebleeding group , The remaining 68 cases were included in the non-bleeding group, statistical analysis of risk factors for early rebleeding after EVS treatment. [Results] There was significant difference in Child-Pugh score, prothrombin time, albumin level, portal vein diameter and serum Na between the two groups (P = 0.037,0.006,0.015,0.026,0.017). Multivariate analysis showed that Child-Pugh score, prothrombin time, portal vein diameter and serum Na value before EVS treatment were independent risk factors for early rebleeding after EVS treatment. [Conclusion] The higher Child-Pugh score, longer prothrombin time, wider portal vein and higher serum Na value may indicate that the risk of early rebleeding after EVS is high.