药物在口腔粘膜上不仅容易被吸收,而且可以避免肝脏的首过作用,为改善药物释放和吸收提供了多种途径,因此,口腔粘贴膜剂的研制已是人们极为关注的领域之一。目前研究膜剂体外释药的速度一般采用片剂溶出速度的 The drug is not only easily absorbed on the oral mucosa, but also can avoid the first pass of the liver and provide a variety of ways to improve the drug release and absorption. Therefore, the development of oral adhesive film has become one of the areas of great concern. The current study of drug release rate in vitro tablet dissolution rate