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自1988年Yanagisawa从猪主动脉内皮细胞分离出内皮素(ET)以来,国内外对ET的基础研究较多。但在临床方面;特别在小儿肾病综合征血浆中的变化研究尚少。 方法和结果 一、资料 1994年8～10月在本院住院的初发和复发的原发性肾病综合征患儿,年龄17月至14岁9例,分别在极期和缓解期测定ET。外科非感染性疾病(如非嵌顿性疝、斜颈、马蹄内翻足、多指畸形)需择期手术者为对照组,共28例。3组间年龄、性别比较无明显差别。
Since 1988, Yanagisawa isolated from porcine aortic endothelial cells endothelin (ET), the basic research on ET at home and abroad more. However, in clinical aspects; especially in children with nephrotic syndrome plasma changes are still few. Methods and Results 1. Data Children with primary nephrotic syndrome who were hospitalized in our hospital from August to October in 1994 and who had primary nephrotic syndrome and were aged from 17 months to 14 years were enrolled in the study. Surgical non-infectious diseases (such as non-incarcerated hernia, torticollis, clubfoot, multi-finger deformity) required elective surgery for the control group, a total of 28 cases. There was no significant difference between the three groups in age and sex.