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应用吸氧 + Bi PAP对 2 3例重叠综合征患者进行康复治疗作为治疗组 ,2 4例单纯吸氧治疗作为对照组。治疗前及 2年后测定彩色多普勒超声心动图。结果 :治疗组肺动脉平均压 ( m PAP)较治疗前下降 ( P<0 .0 5 ) ,对照组则增高 ( P<0 .0 5 )。治疗组 VE提高、VA降低、VE/VA明显增大、RVEF提高 ,与治疗前比较有显著性差异 ( P<0 .0 5 )。对照组RVOTd较前明显增大 ( P<0 .0 5 ) ,同时 RVDd、RVTd、RPAP均有增加 ,但与治疗前比较无显著性差异 ( P>0 .0 5 ) ,而治疗组则变化不大 ( P>0 .0 5 )。提示 :吸氧 + Bi PAP治疗能有效改善重叠综合征患者的夜间缺氧 ,改善右心功能 ,延缓肺心病的发展。
Twenty-three patients with overlap syndrome were treated with oxygen therapy and Bi PAP as the treatment group, and 24 patients with pure oxygen therapy as the control group. Color Doppler echocardiography was performed before and 2 years after treatment. Results: The mean pulmonary artery pressure (m PAP) of the treatment group was significantly lower than that before treatment (P <0.05), while that of the control group (P <0.05). The treatment group, VE increased, VA decreased, VE / VA increased significantly, RVEF increased, compared with before treatment were significantly different (P <0.05). The RVOTd in the control group was significantly increased (P <0.05), while the RVDd, RVTd and RPAP levels increased at the same time, but there was no significant difference between before and after treatment (P> 0.05) Not significant (P> 0.05). Tip: oxygen + Bi PAP treatment can effectively improve patients with overlapping syndrome at night hypoxia, improve right heart function, delay the development of pulmonary heart disease.