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目的了解脂蛋白-胆固醇代谢和妊娠高血压综合征（妊高征）的关系。方法对正常孕妇及妊高征孕妇，分别于妊娠中期、晚期及脐血测定载脂蛋白A(apolipoproteinAPO－A）、载脂蛋白B（apolipoproteinB,APO－B）、高密度脂蛋白-胆固醇（highdensitylipoprotein－choesterol，HDL－C）、低密度脂蛋白-胆固醇（lowdensitylipoprotein－cholesterol，LDL－C）的值。结果APO－A和HDL－C的值妊高征组和正常妊娠组比较，无显著差异。LDL－C和APO－B的值随着妊娠孕周的增加而增高。妊高征组和正常妊娠组相比较，ARJ－B在孕中期、晚期和脐血中的水平妊高征组均高于对照组，均有显著差异；妊高征组LDL－C于孕晚期高于正常妊娠组，P＜0．05。结论低密度脂蛋白-胆固醇代谢异常及高水平和妊高征发病有关。
Objective To understand the relationship between lipoprotein-cholesterol metabolism and pregnancy-induced hypertension (PIH). Methods The levels of apolipoprotein APO-A, apolipoprotein B (APO-B), high-density lipoprotein -choesterol, HDL-C) and low-density lipoprotein-cholesterol (LDL-C). Results APO-A and HDL-C values PIH group and normal pregnancy group, no significant difference. The values of LDL-C and APO-B increased with gestational weeks of gestation. PIH group and normal pregnancy group, ARJ-B in the second trimester, late and cord blood levels of PIH group were higher than the control group, there were significant differences; PIH group LDL-C in the third trimester of pregnancy Higher than normal pregnancy group, P <0.05. Conclusions Low density lipoprotein-cholesterol metabolism is associated with high levels of PIH.