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目的观察含左氧氟沙星方案治疗初治肺结核患者的疗效和安全性。方法采用随机配对分组,将50例初治结核病患者分为治疗组26例和对照组24例。治疗方案:治疗组含左氧氟沙星,两组同时辅以其他相同抗痨药物治疗。结果治疗2个月末、6个月末,治疗组痰菌阴转、病灶吸收、症状改善均明显高于对照组。结论左氧氟沙星具有良好的抗结核作用,可应用于各种类型的肺结核,安全、有效、不良反应小。
Objective To observe the efficacy and safety of levofloxacin regimen in the treatment of newly diagnosed pulmonary tuberculosis patients. Methods Fifty patients with untreated tuberculosis were randomly divided into treatment group (n = 26) and control group (n = 24). Treatment options: treatment group containing levofloxacin, both supplemented by the same anti-tuberculosis drugs. Results At the end of 2 months and 6 months of treatment, the sputum negative conversion, lesion absorption and symptom improvement in the treatment group were significantly higher than those in the control group. Conclusion Levofloxacin has a good antituberculous effect and can be used in various types of pulmonary tuberculosis. It is safe, effective and has a small adverse reaction.