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Objective:To evaluate the antioxidant potential of the phenolic extracts of Mimusops elengi(M.elengi) L.(Sapotaceae).Methods:The extract of stem bark and seeds of M.elengi were prepared in methanol and acefone:water(7:3).The acetone:water was further partitioned with ethyl acetate and n-butanol.Antioxidant activity of the extracts and partitioned fractions of M.elengi was evaluated in terms of radical scavenging potential(DPPH),inhibition of lipid peroxidation[ferric thiocyanate(FTC)],and total antioxidant activity(phosphomolybdate method).Total phenolics content were calculated using Folin-Ciocalteu reagent.Results:The stem bark extract partitioned with ethyl acetate exhibited highest amount ol total phenols(98.0 mg GAE/g dry weight),among all other extracts,with 92.0%DPPH radical scavenging activity al concentration of0.5 mg/mL.while methanol extract(stem bark) had maximum inhibition ol lipid peroxidation(62.0%)and total antioxidant activity(771.0 mg/g GAE/g).A positive correlation occurred between tolal phenols and radical scavenging activity(R~2 = 0.9229) and total antioxidant activity(R~2= 0.9451).Conclusions:Our study suggested that antioxidant activity of stembark extract of M.elengi is due the presence of phenolic compounds.Furthermore,the hark extract is a valuable source of natural antioxidants.
Objective: To evaluate the antioxidant potential of the phenolic extracts of Mimusops elengi (M.elengi) L. (Sapotaceae). Methods: The extract of stem bark and seeds of M. elengi were prepared in methanol and acefone: water (7: 3 ). The acetone: water was further partitioned with ethyl acetate and n-butanol. Antioxidant activity of the extracts and partitioned fractions of M. elengi was evaluated in terms of radical scavenging potential (DPPH), inhibition of lipid peroxidation [ferric thiocyanate (FTC Total phenolics content were calculated using Folin-Ciocalteu reagent. Results: The stem bark extract partitioned with ethyl acetate serving highest amount ol total phenols (98.0 mg GAE / g dry weight), among all other extracts with 92.0% DPPH radical scavenging activity al concentration of 0.5 mg / mL. while methanol extract (stem bark) had maximum inhibition ol lipid peroxidation (62.0%) and total antioxidant activity (771.0 mg / g GAE / g) . A positive correlation o ccurred between tolal phenols and radical scavenging activity (R ~ 2 = 0.9229) and total antioxidant activity (R ~ 2 = 0.9451) .Conclusions: Our study suggested that antioxidant activity of stembark extract of M.elengi is due to the presence of phenolic compounds. Furthermore, the hark extract is a valuable source of natural antioxidants.