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[目的]探究肝硬化失代偿期患者血清钠代谢变化与肝功能Child分级的相关性。[方法]选取我院2009年5月~2015年3月收治的500例肝硬化失代偿期患者,其中300例血钠正常,200例低血钠。对比血钠正常患者与低血钠患者Child A、B、C级所占比例,对比轻、中、重度低血钠患者中Child A、B、C级所占比例。[结果]血钠正常组Child A、C级比例分别与低血钠组比较,组间比较差异有统计学意义(P<0.05)。轻度低钠血症组Child A级比例明显高于中度低钠血症组,Child C级明显低于中度低钠血症组(P<0.05);轻度低钠血症组Child A级比例明显高于重度度低钠血症组,Child C级明显低于重度低钠血症组(P<0.05);中度低钠血症组Child A级比例明显高于重度低钠血症组,Child C级明显低于重度低钠血症组(P<0.05)。[结论]肝硬化失代偿期患者血钠水平越低则患者相应肝功能Child分级等级越高,严密监测血钠水平变化对患者的临床诊治具有重要价值。
[Objective] To investigate the correlation between the change of serum sodium metabolism and Child classification of liver function in patients with decompensated liver cirrhosis. [Method] The 500 patients with decompensated liver cirrhosis admitted from May 2009 to March 2015 in our hospital were selected, of whom 300 had normal serum sodium and 200 had hyponatremia. The proportions of Child A, B and C in normal and hyponatremia patients were compared, and the proportions of Child A, B and C in mild, moderate and severe hyponatremia were compared. [Result] Compared with hyponatremia group, the levels of Child A and C in serum sodium normal group were significantly different (P <0.05). Child A grade in mild hyponatremia group was significantly higher than that in moderate hyponatremia group, and Child C grade was significantly lower than that in moderate hyponatremia group (P <0.05); Child A The level of Child A was significantly higher than that of severe hyponatremia, and Child C was significantly lower than that of severe hyponatremia (P <0.05). The Child A grade of moderate hyponatremia was significantly higher than that of severe hyponatremia Group, Child C level was significantly lower than severe hyponatremia group (P <0.05). [Conclusion] The lower the level of serum sodium in patients with decompensated cirrhosis is, the higher the grade of Child corresponding to liver function is. The close monitoring of serum sodium level is of great value in the clinical diagnosis and treatment of patients.