在常见的恶性肿瘤中,肺癌、乳腺癌和前列腺癌等常发生骨转移,导致顽固性疼痛。骨痛令病人痛苦不堪,活动受限,生活质量恶化。病人往往因剧痛而失去治疗信心。以往治疗骨转移性疼痛常用的方法为化疗、放疗及阶梯性使用止痛药物等,但对广泛骨转移者疗效并不理想。近年来,国内外将 In common malignancies, bone metastases such as lung cancer, breast cancer and prostate cancer often lead to intractable pain. Bone pain makes the patient suffering, activities are limited, quality of life deteriorated. Patients often lose treatment confidence due to severe pain. In the past, the commonly used methods for the treatment of bone metastatic pain were chemotherapy, radiotherapy and step-by-step analgesic drugs, but the effect was not satisfactory for a wide range of bone metastases. In recent years, both at home and abroad will be