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目的:评价角膜塑形术(Orthokeratology)治疗青少年近视的效果。方法:应用角膜塑形术治疗56例青少年近视患者共110眼。分为3组:Ⅰ组为-1.00～3.00D,Ⅱ组为-3.25～-6.00D,Ⅲ组为-6.25～-7.50D,随访3个月。将各个时期的裸眼视力、屈光度、角膜屈光力与术前进行比较。同时,对治疗3个月后的角膜屈光力变化值(X)与临床屈光度变化值(Y)进行直线回归及直线相关分析。结果:3组患者术后1天、1周、1月、2月、3月裸眼视力均比术前显著提高(P<0.01);屈光度随疗程明显下降(P<0.01);角膜屈光力均比术前明显降低(P<0.01);角膜屈光力变化与临床屈光度变化呈正相关,相关系数r=0.381,P<0.001。结论:角膜塑形术是治疗青少年近视的一种安全有效的方法,远期疗效尚有待观察。眼科学报2000;16:149-152。
Objective: To evaluate the effect of Orthokeratology in the treatment of juvenile myopia. Methods: Fifty-six eyes of adolescents with myopia were treated with orthokeratology. Divided into three groups: Ⅰ group was -1.00 ~ 3.00D, Ⅱ group was -3.25 ~ -6.00D, Ⅲ group was -6.25 ~ -7.50D, followed up for 3 months. The various periods of uncorrected visual acuity, refraction, corneal refractive power and preoperative comparison. At the same time, the linear regression and linear correlation analysis were performed on the change of corneal power (X) and the value of clinical refraction (Y) after 3 months of treatment. Results: The uncorrected visual acuity of the three groups was significantly higher than that before operation (P <0.01) at 1 day, 1 week, 1 month, 2 months and 3 months after operation. The diopter decreased with the course of treatment (P <0.01) (P <0.01). There was a positive correlation between corneal refractive power and clinical refraction (r = 0.381, P <0.001). Conclusion: Orthokeratology is a safe and effective method for the treatment of juvenile myopia. The long-term therapeutic effect remains to be seen. Journal of Ophthalmology 2000; 16: 149-152.