Silica, alumina, and activated carbon supported iron-cobalt catalysts were prepared by incipient wetness impregnation. These catalysts have been characterized by BET, X-ray diffraction (XRD), and temperature-programmed reduction (TPR). Activity and selectivity of iron-cobalt supported on different carriers for CO hydrogenation were studied under the conditions of 1.5 MPa, 493 K, 630 h-1, and H2/CO ratio of 1.6. The results indicate that the activity, C4 olefin/(C4 olefin+C4 paraffin) ratio, and C5 olefin/(C5 olefin+C5 paraffin) decrease in the order of Fe-Co/SiO2, Fe-Co/AC1, Fe-Co/Al2O3 and Fe-Co/AC2. The activity of Fe-Co/SiO2 reached a maximum. The results of TPR show that the Fe-Co/SiO2 catalyst is to some extent different. XRD patterns show that the Fe-Co/SiO2 catalyst differs significantly from the others; it has two diffraction peaks. The active spinel phase is correlated with the supports. Silica, alumina, and activated carbon supported iron-cobalt catalysts were prepared by incipient wetness impregnation. These catalysts have been characterized by BET, X-ray diffraction (XRD), and temperature-programmed reduction cobalt supported on different carriers for CO hydrogenation were studied under the conditions of 1.5 MPa, 493 K, 630 h-1, and H2 / CO ratio of 1.6. The results indicate that the activity, C4 olefin / (C4 olefin + C4 paraffin) (C5 olefin + C5 paraffin) decrease in the order of Fe-Co / SiO2, Fe-Co / AC1, Fe-Co / Al2O3 and Fe-Co / AC2. The activity of Fe-Co / SiO2 reached a maximum. The results of TPR show that the Fe-Co / SiO2 catalyst is to some extent different. XRD patterns show that the Fe-Co / SiO2 catalyst differs significantly from the others; it has two diffraction peaks. The active spinel phase is correlated with the supports.