目的:优选甜荞麦花叶中芦丁的最佳提取工艺。方法:采用高效液相色谱技术,以荞麦花叶中所含的主要有效成分芦丁的含量为评价指标,采用L9(34)正交试验法,通过超声波辅助提取技术,考察了药材的粉碎度、所用溶剂、提取时间、提取次数四因素对荞麦芦丁提取率的影响。结果:药材为细粉、溶剂选用甲醇、提取时间60min、提取次数3次提取效果最好。结论:本实验为优化荞麦花叶中芦丁的提取工艺提供了参考依据。 Objective: To optimize the extraction process of rutin in sweet buckwheat mosaic leaf. Methods: The content of rutin, the main active ingredient in the buckwheat flower mosaic, was evaluated by high performance liquid chromatography (HPLC), using orthogonal design of L9 (34) to study the degree of comminution , Solvent used, extraction time, the number of extraction four factors on the yield of buckwheat rutin. Results: The medicinal material was fine powder, the solvent was methanol, the extraction time was 60min, the extraction time was 3 times and the extraction effect was the best. Conclusion: This experiment provides a reference for optimizing the extraction process of rutin in buckwheat flower.