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目的分析研究皮肤钙化上皮瘤的临床及组织病理特点。方法回顾性2009年6月-2012年6月在我院治疗的17例皮肤钙化上皮瘤患者的临床资料。结果患者病变以头面部、上肢为主,肿瘤直径0.32-2.0cm,临床误诊率达64.71%(11/17);肿瘤大部分有包膜,由嗜碱性细胞和影子细胞组成,间质由纤维结缔组织构成,伴有不同程度的钙化和炎症细胞浸润。结论临床医生应增强对皮肤钙化上皮瘤临床病理特征的认识,以提高对此病诊断的正确率。
Objective To analyze the clinical and histopathological features of skin calcified epithelial tumors. Methods The clinical data of 17 patients with cutaneous calcified epithelioma treated in our hospital from June 2009 to June 2012 were retrospectively reviewed. Results The patient’s lesions were chiefly head and face and upper limbs. The tumor diameter was 0.32-2.0 cm. The clinical misdiagnosis rate was 64.71% (11/17). The tumors were mostly enveloped and composed of basophils and shadow cells. Fibrous connective tissue, with varying degrees of calcification and inflammatory cell infiltration. Conclusions Clinicians should enhance their understanding of the clinicopathological features of cutaneous calcified epithelial tumors in order to improve the diagnostic accuracy of this disease.