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目的分析对产后出血患者采用米索前列醇进行治疗的效果,并对其药理作用进行解析。方法 240产妇作为临床研究对象分为治疗组和对照组,各60例,娩出胎儿后,对照组给予缩宫素,治疗组给予米索前列醇治疗;将120例产妇分为A、B、C三组,各40例,A组直肠给药,B组舌下含服,C组阴道给药。结果治疗组患者的产程明显短于对照组差异有统计学意义(P<0.05);治疗组患者的术后3 h出血量与术后1 d出血量明显少于对照组差异有统计学意义(P<0.05);不同给药方法对产妇的各项指标影响较小,差异无统计学意义(P>0.05)。结论采用米索前列醇治疗产后出血,能够显著减少产妇出血量,降低不良反应,药理作用较为明显,值得临床推广。
Objective To analyze the effect of misoprostol on postpartum hemorrhage and to analyze its pharmacological effects. Methods 240 maternal women were divided into treatment group and control group with 60 cases each. After the fetus was delivered, the control group was given oxytocin and the treatment group was treated with misoprostol. 120 maternal women were divided into A, B and C Three groups, each 40 cases, group A rectum, group B sublingual, group C vaginal administration. Results The length of labor was significantly shorter in the treatment group than in the control group (P <0.05). The bleeding volume at 3 h after operation and the bleeding volume at 1 d after operation in the treatment group were significantly lower than those in the control group P <0.05). There was no significant difference in the indexes of maternal by different administration methods (P> 0.05). Conclusion Misoprostol treatment of postpartum hemorrhage, can significantly reduce the amount of maternal bleeding, reduce adverse reactions, pharmacological effects are more obvious, worthy of clinical promotion.