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目的:对淄博市新报告人类免疫缺陷病毒（human immunodeficiency virus，HIV）/获得性免疫缺陷综合征（acquired immunodeficiency syndrome，AIDS）病例外周血T淋巴细胞亚群进行检测分析，了解其免疫水平及疾病进展情况。方法:采集2015年1月至2017年12月淄博市疾病预防控制中心确证的250例新报告的HIV/AIDS患者抗凝全血，用流式细胞仪检测T淋巴细胞亚群，所得数据用SPSS 16.0软件进行统计分析。结果:250例HIV/AIDS样本的传播途径均为性接触，首次检测其外周血CD4n + T淋巴细胞绝对数均值为（348.99±204.21）个/μL。不同年龄组间CD4n + T淋巴细胞均值、CD8n + T淋巴细胞均值和CD4n +/CD8n +的比值差异均有统计学意义（n P60岁组比较差异有统计学意义（n P350个/μL组例数比较差异有统计学意义（n P<0.05）。n 结论:淄博市新报告HIV/AIDS病例外周血CD4n + T淋巴细胞水平普遍偏低。应进一步加强宣传干预，重点加强老年人艾滋病的防控和干预工作。n “,”Objective:To detect and analyze peripheral blood T-lymphocyte subsets in newly reported human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) cases in Zibo city, so as to estimate the level of HIV/AIDS immunity status and disease progression in the city.Methods:A total of 250 anticoagulated whole blood samples of newly reported HIV/AIDS cases were collected. The absolute value and percentage of T-lymphocyte sub-populations were detected by flow cytometry. The data were analyzed by SPSS 16.0 software.Results:The transmission routes of 250 HIV/AIDS case were sexual contact. The mean value of CD4n + T-lymphocyte in the newly reported cases was 348.99±204.21 cells/μL. The differences in mean values of CD4n + T-lymphocyte, CD8n + T-lymphocyte and CD4n +/CD8n + ratios were all statistically significant respectively among different age groups (n P60-years-old group were statistically significantly ( n P350 cells/μL in different household registrations, ages and populations ( n P<0.05).n Conclusions:The CD4n + T-lymphocytes in peripheral blood were generally low in newly reported HIV/AIDS cases in Zibo city. Publicity and intervention should be strengthened, focusing on the prevention and control of AIDS among the elderly.n