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急性有机磷农药中毒为基层医院常见的内科急症之一,死亡率极高。我科自1992～1999年共收治急性有机磷农药中毒242例,其中35例死亡,现就其死亡原因分析如下。1 临床资料1.1 一般情况:本组病人35例,均为口服有机磷农药中毒,其中男性12例,女性23例,年龄为18～78岁,平均年龄48岁。口服敌敌畏者15例,敌杀死者5例,乐果者8例,对硫磷者5例。35例病人入院前均是昏迷状态或意识朦胧,口服有机磷农药量在100～500ml,全部病人均在服药后30分钟～6小时入院。1.2 治疗与结果:立即给予洗胃,静推阿托品,首次量为10～20mg,每2分钟1次。同时应用解磷定、补液、利尿、对症,吸氧,应用呼吸兴奋剂等抢救措施。结果35例死亡患者分别于入院1天内死亡20例;2天以内死亡7例;3天以内死亡5例;4天内死亡2例。
Acute organophosphorus pesticide poisoning is one of the common medical emergencies in primary hospitals, with a high mortality rate. Our department from 1992 to 1999, a total of 242 cases of acute organophosphorus pesticide poisoning, of which 35 died, the cause of death are now analyzed as follows. 1 Clinical data 1.1 General situation: The group of 35 patients were oral organophosphorus pesticide poisoning, including 12 males and 23 females, aged 18 to 78 years, mean age 48 years. Oral dichlorvos in 15 cases, the enemy killed 5 cases, 8 cases of dimethoate, parathion in 5 cases. All 35 patients were unconscious or obscured before admission. Oral doses of organophosphorus pesticides ranged from 100ml to 500ml. All patients were admitted for 30 minutes to 6 hours after taking the drug. 1.2 treatment and results: Immediate gastric lavage, static push atropine, the first dose of 10 ~ 20mg, every 2 minutes 1. At the same time the application of phosphate solution, fluid, diuretic, symptomatic, oxygen, the application of respiratory stimulants and other rescue measures. Results 35 patients died in 20 days admitted to hospital within 1 day; 7 cases died within 2 days; 5 cases died within 3 days; 2 cases died within 4 days.