角化棘皮瘤(KA)的治疗方法有多种,最常用的是外科手术切除,它具有一次性治愈的优点,并能提供完整的标本做组织活检,但缺点是美容效果不佳可能需要整形,尤其是对面部的KA。作者用甲氨喋呤(MTX)损害部位内注射治疗鼻部KA 2例,效果显著。 例1,男,66岁,短期内鼻左侧出现肿物,迅速增大直径为1.5cm,边缘坚实卷曲,炎性基质中央充填角栓,临床诊断为典型的KA。使用 There are many ways to treat keratoacanthoma (KA), the most commonly used is surgical resection, which has the advantage of a one-time cure and can provide a complete specimen for tissue biopsy, but the disadvantage is the poor cosmetic results may require plastic surgery , Especially for face KA. The author of methotrexate (MTX) damage within the site of the treatment of nasal KA 2 cases, the effect is significant. Example 1, male, 66 years old, short-term nasal left side of the tumor, the rapid increase in diameter of 1.5cm, solid curly edge, the central filling of inflammatory matrix plug, clinically diagnosed as a typical KA. use