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在研究植物或植物药的化学成分或有效成分时,即使采用温和的条件进行提取分离,亦可发生化学反应,而导致化学结构的显著变化。这是一个必须加以重视的问题,因为化学结构上的微小变化,对其化学和物理属性,可能变化不大,而生理活性往往会产生截然不同的效果,甚至产生恰巧相反的生理活性。下面举出一些事例,说明在一般的提取、分离、精制等过程中,同一些环境因素和化学试剂包括阳光、空气、酸碱、溶剂以及吸附剂等的接触,可引起某些化学反应而导致化学结构上的显著变化。虽然原文献多未探讨其变化反应机理过程,有些尚不知是何种因素引起的,但已足以说明即使是在十分谨慎的处理条件下,也很有可能引起某些成分结构上的变化。
When studying the chemical composition or active ingredient of a plant or botanical drug, chemical reactions may occur even if the extraction and separation are performed under mild conditions, resulting in a significant change in the chemical structure. This is a problem that must be taken into account. Because of the small changes in chemical structure, its chemical and physical properties may not change much, and physiological activity tends to produce completely different effects, even producing the exact opposite of physiological activity. Here are some examples that show that in general extraction, separation, and purification processes, contact with some environmental factors and chemical agents including sunlight, air, acids, bases, solvents, and adsorbents can cause certain chemical reactions and cause Significant changes in chemical structure. Although the original literature has not discussed the process of its change reaction mechanism, some do not know what caused the cause, but it is enough to explain that even under very cautious treatment conditions, it is very likely to cause structural changes in some components.