论文部分内容阅读
目的探讨长效胰岛素应用时间对糖尿病患者空腹血糖控制的临床效果。方法选取在我院接受治疗的糖尿病患者82例,随机分为对照组46例,治疗1组19例,治疗2组17例。对照组采用进口赖普胰岛素和中效胰岛素(诺和灵N)进行联合治疗。治疗1组和2组均采用甘精胰岛素(来得时)素进行治疗。结果治疗后,3组患者的空腹血糖、餐后2小时血糖均比本组治疗前有显著降低(P<0.05),同时,比较三组患者治疗后的以上项指标,均无显著性差异,不具有统计学意义(P>0.05)。治疗过程中,治疗1组和治疗2组的低血糖发生率分别为5.26%、0,明显低于对照组的34.78%(P<0.05)。结论长效胰岛素的应用时间不影响糖尿病患者的空腹血糖控制效果,但提倡老年人应选择白天用药。
Objective To investigate the clinical effect of long-acting insulin on the fasting blood glucose control in diabetic patients. Methods Totally 82 diabetic patients treated in our hospital were randomly divided into control group (n = 46), treatment group (n = 19) and treatment group (n = 2). The control group was treated with imported rapamycin and mid-acting insulin (noradrenaline N). Treatment 1 and 2 were treated with insulin glargine (h). Results After treatment, the fasting blood glucose and 2-hour postprandial blood glucose of the three groups were significantly lower than those before treatment (P <0.05). At the same time, there was no significant difference between the three groups after treatment, Not statistically significant (P> 0.05). During the course of treatment, the incidences of hypoglycaemia in treatment group 1 and treatment group 2 were 5.26% and 0, respectively, which were significantly lower than those in control group (34.78%, P <0.05). Conclusion Long-acting insulin application time does not affect the fasting blood glucose control in patients with diabetes, but the elderly should advocate the choice of daytime medication.