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目的:通过比较重度子痫前期诱发的胎盘早剥孕妇血清中CAl25及AFP水平探讨其对胎盘早剥早期诊断的临床应用价值。方法:选取72例重度子痫前期孕妇作为研究对象,其中45例患者伴有胎盘早剥,采用微粒酶免疫分析法检测孕妇血清中CAl25、AFP水平,并对结果进行比较分析。结果:重度子痫前期合并胎盘早剥组CAl25和AFP为(231.4±53.1)U/ml和(357.2±78.5)mg/ml比单纯重度子痫前期组(117.6±76.3)U/ml和(273.4±82.9)mg/ml明显升高,差异有统计学意义(P<0.01)。结论:血清中CAl25及AFP等生化参数可以作为胎盘早剥的预测及早期诊断的实验室检查指标,具体数值标准仍需进一步论证。
OBJECTIVE: To compare the serum levels of CA125 and AFP in placental abruption pregnant women induced by severe preeclampsia and to explore its clinical value in the early diagnosis of placental abruption. Methods: Seventy-two pregnant women with severe preeclampsia were selected as the research object. Forty-five pregnant women with placental abruption were involved in this study. The serum levels of CA125 and AFP in pregnant women were detected by the enzyme-linked immunosorbent assay (ELISA), and the results were compared. Results: Compared with the severe preeclampsia group (117.6 ± 76.3) U / ml and (273.4), the levels of CA125 and AFP in severe preeclampsia and placental abruption group were (231.4 ± 53.1) U / ml and (357.2 ± 78.5) ± 82.9) mg / ml, the difference was statistically significant (P <0.01). Conclusion: Serum CAl25 and AFP biochemical parameters such as biochemical parameters can be used as a prediction of early placental abruption and laboratory test indicators, the specific numerical criteria still need further proof.