目的　探讨转化细胞特性及与致瘤性的关系。方法　广泛查阅近期有关转化细胞和致瘤性方面的文献,综述其内容。结果　一般转化细胞无致瘤性,大都能保持其正常细胞的生物学特性和功能,而恶性转化细胞其生物学特性和功能明显改变。结论　无致瘤性的一般转化细胞可作为标准细胞研究正常细胞的生理功能及其相关特性 Objective To investigate the relationship between the characteristics of transformed cells and tumorigenicity. Methods Extensive reviews of recent literature on transformed cells and oncogenicity are summarized and reviewed. The results of the general transformation of non-tumorigenic cells, most of them can maintain the biological characteristics and function of normal cells, and malignant transformed cells of its biological characteristics and function significantly changed. Conclusion The non-neoplastic general transformed cells can be used as standard cells to study the physiological functions of normal cells and their related properties