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本文用敏感的方法检测北京、广西地区不同年龄正常人群和不同肝病患者中之HBsAg、抗-HBs、HBeAg、抗-HBe,发现北京地区以2岁以下组HBsAg阳性率最高(12.4%),抗-HBs随年龄增长而增高。广西地区以4岁以下组HBsAg阳性率最高达21.6%。两者HBsAg阳性中HBeAg阳性率分别为59.2%及77.5%;抗-HBe为11.1%及15.O%。在两地不同慢性肝炎、肝硬化、肝癌患者与HBV感染密切相关,患者组明显高于对照组。孕妇中HBsAg阳性率为6.7%,其中HBeAg阳性为43.2%,用HBIG及乙肝疫苗联合阻断,婴儿全部产生抗-HBs。
In this paper, HBsAg, anti-HBs, HBeAg and anti-HBe in Beijing and Guangxi areas of different age groups and patients with different liver diseases were detected by sensitive method. The highest positive rate of HBsAg (12.4%) was found in Beijing under 2 years old HBs increase with age. Guangxi area to 4 years of age group HBsAg positive rate up to 21.6%. The positive rates of HBeAg in both HBsAg positive patients were 59.2% and 77.5% respectively, while that of anti-HBe was 11.1% and 15.0% respectively. In the two different chronic hepatitis, cirrhosis, liver cancer patients with HBV infection is closely related to the patient group was significantly higher than the control group. The positive rate of HBsAg in pregnant women was 6.7%, of which HBeAg positive was 43.2%. Combined with HBIG and hepatitis B vaccine, the infants all produced anti-HBs.