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采用萘酚AS—MX法测定106例不同疾病的新生儿和正常新生儿的白细胞碱性磷酸酶（LAP）活性，并计数白细胞总数和分类。结果细菌性感染组LAP活性明显高于对照组、非感染组和病毒组，差异有非常显著意义（P＜0．01）；病毒性疾病组LAP活性明显低于对照组（P＜0．05）。提示LAP活性是诊断新生儿细昏性疾病有意义的检测指标，而且对鉴别细菌和病毒性感染有一定的临床价值。
The neutrophil alkaline phosphatase (LAP) activity of 106 neonates with different diseases and normal neonates was measured by the naphthol AS-MX method, and the total number and classification of leukocytes were counted. Results The LAP activity in bacterial infection group was significantly higher than that in control group, non-infected group and virus group (P <0.01). The LAP activity in viral disease group was significantly lower than that in control group (P <0.05) ). It is suggested that LAP activity is a useful indicator in the diagnosis of neonatal drowsiness and has some clinical value in differential diagnosis of bacterial and viral infections.