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目的探讨来源于妇科而被误诊为消化道癌的肿瘤病理形态及免疫组化特征。方法回顾分析我院3例妇科原发性癌被误诊为消化道癌的病理资料并文献复习。结果 3例均无妇科肿瘤病史,因以消化道为首发症状而被误诊为消化道癌。后经免疫组化证实来源于妇科的转移性癌。其中2例原发于卵巢,1例原发于子宫,以浆液性癌和宫内膜样癌为主要组织类型,分别转移至乙状结肠(1例)、直肠(2例)。结论发生于中老年妇女的下消化道肿瘤,尤其对病史不详、治疗效果不佳时,应排除妇科肿瘤转移的可能,病理诊断应结合临床资料、肿瘤组织形态及免疫组化特征。
Objective To investigate the tumor histopathology and immunohistochemical characteristics of gynecological patients who have been misdiagnosed as gastrointestinal cancer. Methods Retrospective analysis of 3 cases of primary gynecological cancer in our hospital was misdiagnosed as gastrointestinal cancer pathological data and literature review. Results All three cases had no history of gynecologic oncology, which was misdiagnosed as digestive tract cancer due to digestive tract as the first symptom. After immunohistochemistry confirmed gynecological metastatic cancer. Two of them were primary in the ovary and one in the uterus. Serous and endometrial carcinomas were the main histological types, which were transferred to sigmoid colon (1 case) and rectum (2 cases). Conclusions Occurred in the lower gastrointestinal cancer in elderly women, especially for the history is unknown, the treatment effect is poor, the possibility of gynecologic tumor metastasis should be ruled out, pathological diagnosis should be combined with clinical data, tumor morphology and immunohistochemical characteristics.