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暴发性肝功能衰竭时,消化道粘膜糜烂,同时有凝血障碍,故胃肠道出血常超过50％。作者选择了75例Ⅳ度昏迷的暴发性肝功能衰竭患者(服用过量扑热息痛39例、急性病毒性肝炎32例、氟烷麻醉4例),分别使用制酸剂和组织胺H_2受体拮抗剂治疗,以观察它们对这类消化道出血的预防作用。全部病例无1例有胃肠道出血的临床证据。药物剂量:13例用氢氧化镁每4小时从鼻胃管注入20毫升。26例用组织胺H_2受体拮抗剂,其中10例用甲
Outbreaks of liver failure, gastrointestinal mucosal erosion, while coagulation disorders, it often more than 50% of gastrointestinal bleeding. The authors selected 75 patients with fulminant grade IV coma who had fulminant hepatic failure (39 acetaminophen overdosed, 32 with acute viral hepatitis, and 4 with halothane) were treated with antacids and histamine H 2 receptor antagonists In order to observe their preventive effect on such gastrointestinal bleeding. None of the cases had clinical evidence of gastrointestinal bleeding. Drug dose: Thirteen patients were injected with 20 ml of magnesium hydroxide from the nasogastric tube every 4 hours. 26 patients with histamine H 2 receptor antagonists, of which 10 cases with a