我们应用尿激酶治疗肾病综合征(NS)20例(年龄13～52岁),其中原发性NS18例,狼疮性肾病2例。临床分型为Ⅰ型12例,Ⅱ型8例。实验室检查:尿蛋白(卅～卌),24小时尿蛋白定量>3.5g,最高达26g,血浆白蛋白均<30g/L,血纤维蛋白原3.8～8.7g/L,平均6.15g/L。另选18例NS病人做对照,其年龄、临床分型与治疗组相似。 治疗方法:治疗组用强的松+潘生丁+PSS+尿激酶。尿激酶用法为:10万～20万U加入5％葡萄糖液200ml中静滴,每日2次,共3天;以后改为尿激酶6万～10万U加入5％葡萄糖液中滴,每日1次,14天为一疗程。必要时再行一疗程。对照组除未用尿激酶外,其它同治疗组。两组部分病人 We apply urokinase treatment of nephrotic syndrome (NS) 20 cases (13 to 52 years of age), of which 18 cases of primary NS, lupus nephropathy in 2 cases. Clinical classification of type Ⅰ in 12 cases, type Ⅱ in 8 cases. Laboratory tests: urine protein (卅 ~ 卌), 24-hour urinary protein quantification> 3.5g, up to 26g, plasma albumin <30g / L, fibrinogen 3.8 ~ 8.7g / L, an average of 6.15g / L . Another 18 cases of NS patients do the control, its age, clinical type and treatment group similar. Treatment: The treatment group with prednisone + dipyridamole + PSS + urokinase. Urokinase usage: 100000 ~ 200000 U join 5% glucose solution 200ml intravenous infusion, 2 times a day for 3 days; later changed to urokinase 60,000 ~ 100,000 U by adding 5% glucose solution drops, each Day 1, 14 days for a course of treatment. If necessary, take another course of treatment. In addition to urokinase control group, the other with the treatment group. Two groups of patients