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目的 :探讨溶栓治疗对急性心肌梗死 (AMI)患者急性期和远期运动耐量的影响。方法 :将 143例 AMI患者分为溶栓再通组 (35例 )、未通组 (2 3例 )和非溶栓组 (85例 ) ,比较三组急性期和远期运动耐量。结果 :急性期 ,再通组的运动量、运动时间、最大心率、心率血压乘积均明显高于未通组和非溶栓组 (P<0 .0 5 ) ,运动诱发的心绞痛或血压下降≥ 10 m m Hg(1m m Hg=0 .133k Pa)的比率明显低于后两者 (P <0 .0 5 )。远期随访 ,三组的运动量、最大心率、运动时间、心率血压乘积及运动诱发心绞痛或血压下降的比率均无显著性差异 (P >0 .0 5 )。结论 :溶栓再通能显著提高 AMI患者急性期运动耐量 ,但对远期运动耐量改善不明显
Objective: To investigate the effect of thrombolytic therapy on acute and long-term exercise tolerance in patients with acute myocardial infarction (AMI). Methods: A total of 143 AMI patients were divided into thrombolytic group (35 cases), unreasonable group (23 cases) and non-thrombolytic group (85 cases). The acute and long-term exercise tolerance were compared between the three groups. Results: The product of exercise, exercise time, maximum heart rate, heart rate and blood pressure were significantly higher in the re-intervention group than those in the failed group and the non-thrombolytic group (P <0.05), angina pectoris or blood pressure drop ≥10 mm Hg (1m Hg = 0.133k Pa) was significantly lower than the latter two (P <0.05). Long-term follow-up, there was no significant difference in the amount of exercise, maximum heart rate, exercise time, heart rate blood pressure and exercise-induced angina or decreased blood pressure in the three groups (P> 0.05). Conclusion: Thrombolytic recanalization can significantly improve exercise tolerance in acute phase of AMI patients, but there is no obvious improvement in long-term exercise tolerance