论文部分内容阅读
目的:探讨放射性核素骨显像在儿童Langerhans细胞组织细胞增生症中的研究价值。方法:回顾性分析了40例LCH患儿放射性核素骨显像结果,其中16例患儿进行2～4次随访显像。结果:40例LCH患儿骨显像阳性33例,阳性率82.5%。其中单发病灶者15例,多发病灶者18例。颅骨阳性者15例,以顶骨和颞骨最常受累;四肢长骨阳性者7例,受累的部位依次为股骨、肱骨和胫骨,主要累及骨干部;脊柱阳性者8例,肋骨阳性者2例,髂骨1例。16例随访显像除1例无明显改善,1例缓解后又复发外,14例显像浓聚程度明显减轻。结论:放射性核素骨显像在儿童Langer-hans细胞组织细胞增生症中的诊疗和随访价值较大,有利于评估疗效。
Objective: To investigate the value of radionuclide bone imaging in childhood Langerhans cell histiocytosis. Methods: The results of radionuclide bone imaging in 40 children with LCH were retrospectively analyzed. Among them, 16 children were followed up for 2 to 4 times. Results: The bone imaging of 40 cases of LCH patients was positive in 33 cases, the positive rate was 82.5%. Including single lesions in 15 cases, 18 cases of multiple lesions. Skull positive in 15 cases, the most common involvement of the parietal and temporal bone; limb long bone positive in 7 cases, the affected parts followed by the femur, humerus and tibia, mainly involving the backbone; spine positive in 8 cases, rib-positive in 2 cases, iliac Bone in 1 case. 16 cases of follow-up imaging in 1 case no significant improvement, 1 case of relapse after remission, 14 cases of imaging concentration was significantly reduced. Conclusion: Radionuclide bone imaging in children Langer-hans cell histiocytosis in the diagnosis and follow-up of more valuable to assess the efficacy.