目的分析恙虫病的临床特点,为早期诊断及治疗提供依据。方法通过回顾性分析72例恙虫病患者的临床资料,分析其临床特点。结果所有患者均有发热,发生率为100%;嗜酸性粒细胞比值低于正常者97.2%,其中,嗜酸性粒细胞比值为0者占68.1%,治疗后均可升至正常;伴发肝功能异常者95.8%,均加用护肝药物治疗,其中4例患者5~7 d后复查ALT或AST较前改善不明显甚至有加重;所有患者均选用阿奇霉素或克林霉素治疗,有效率100%。结论恙虫病临床表现多样,嗜酸性粒细胞比值为0以及合并肝功能受损可能对于诊断有一定的意义。阿奇霉素或克林霉素可用于恙虫病的治疗,疗效确切、不良反应少但需注意可能出现的药物性肝损。 Objective To analyze the clinical features of scrub typhus and provide basis for early diagnosis and treatment. Methods The clinical data of 72 patients with scrub typhus were retrospectively analyzed and their clinical features were analyzed. Results All patients had fever, the incidence was 100%; eosinophils were lower than the normal 97.2%, of which eosinophils were 0% accounted for 68.1%, after treatment can rise to normal; associated with liver 95.8% of patients with abnormal function were treated with hepatoprotective drugs, of which 4 patients 5 to 7 days after the review of ALT or AST compared with the previous improvement was not obvious or even worse; all patients were treated with azithromycin or clindamycin, the effective rate 100%. Conclusion The clinical manifestations of scrub typhus are diverse, with eosinophil ratio of 0 and impaired hepatic function may be of some value in the diagnosis. Azithromycin or clindamycin can be used for the treatment of scrub typhus, curative effect is accurate, less adverse reactions, but pay attention to possible drug-induced liver damage.