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目的探讨卡孕栓联合缩宫素、葡萄糖酸钙预防产后出血的临床疗效。方法将112例足月妊娠产妇的随机分为对照组和治疗组各56例,对照组单纯应用缩宫素,治疗组在对照组基础上加用卡孕栓和葡萄糖酸钙,对两组产妇用药后相关临床指标进行分析比较。结果治疗组第三产程时间短于对照组,产后出血量少于对照组,两组比较差异均有统计学意义(P<0.05);两组药物不良反应,用药前后收缩压、舒张压及心率均差异无统计学意义(P>0.05);对照组用药24h后血红蛋白(Hb)下降幅度较治疗组差异有统计学意义(P<0.05)。结论卡孕栓、缩宫素及葡萄糖酸钙联合用药可减少产后出血量及缩短第三产程,是预防产后出血的有效措施,值得基层医院推广应用。
Objective To investigate the clinical efficacy of carbamazepine combined with oxytocin and calcium gluconate in preventing postpartum hemorrhage. Methods One hundred and twelve cases of full-term pregnant women were randomly divided into control group and treatment group, with 56 cases in each group. Oxytocin alone was used in the control group. In the control group, carbapenem and calcium gluconate were added on the basis of the control group. After treatment of relevant clinical indicators for analysis and comparison. Results The duration of the third stage of labor in the treatment group was shorter than that in the control group, and the amount of postpartum hemorrhage was less than that in the control group. The differences between the two groups were statistically significant (P <0.05). The adverse drug reaction, systolic blood pressure, diastolic blood pressure and heart rate (P> 0.05). The decrease of hemoglobin (Hb) in the control group after 24 hours treatment was significantly different from that in the treatment group (P <0.05). Conclusions Combination of carbamazepine, oxytocin and calcium gluconate can reduce the amount of postpartum hemorrhage and shorten the third stage of labor. It is an effective measure to prevent postpartum hemorrhage and is worth popularizing and applying in primary hospitals.