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分析了我院住院治疗的39例铀矿工人肺癌患者的临床数据。并以同期住院的20例未接触过铀的男性肺癌患者的临床资料作对照。铀矿工肺癌患者发病年龄为36～61岁,平均发病年龄为48.8岁,比对照组年龄(57.3岁)早9年(P<0.05),其中21例为接触氡及其子体的井下铀矿工。右肺发病率高于左肺(其比率为2.5:1),以鳞癌为主(53.3%),其次为未分化小细胞癌,而对照组鳞状上皮癌、腺癌相等。平均生存期无明显差别。本组资料中平均井下铀矿工工龄为11.1±5.2年,有剂量资料的11例,受照剂量≥0.504J的5例,经分析认为50%的铀矿工人的肺癌主要是氡及其子体引起,发生肺癌的最低剂量为0.504J(120WLM)。
The clinical data of 39 cases of uranium miners lung cancer hospitalized in our hospital were analyzed. The clinical data of 20 hospitalized patients with lung cancer without uranium were compared. The incidence of lung cancer among uranium miners ranged from 36 to 61 years with a mean age at onset of 48.8 years (9 years, compared with 57.3 years in the control group (P <0.05), of which 21 were underground miners exposed to radon and its progenies . The incidence of right lung was higher than that of the left lung (the ratio was 2.5: 1), mainly squamous cell carcinoma (53.3%), followed by undifferentiated small cell carcinoma, while squamous cell carcinoma and adenocarcinoma were equal in the control group. There was no significant difference in mean survival. In this group of data, the average underground uranium miners ’service age is 11.1 ± 5.2 years. There are 11 cases with dose data and 5 cases received dose ≥0.504 J. According to the analysis, 50% of the uranium miners’ lung cancer is mainly radon and its progeny The lowest dose of lung cancer that occurred was 0.504 J (120 WLM).