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目的:讨论创面负压治疗促进肝硬化合并糖尿病并发糖尿病足的临床疗效。方法:将30例慢性肝硬化合并糖尿病并发糖尿病足患者随机分为创面负压治疗组和敷料包扎组,观察两组创面细菌负荷及创面微循环血流量变化。结果:清创即刻,负压创面治疗组和敷料包扎组细菌负荷与创面微循环血流量无显著差异(P>0.01);创后3天、6天和9天时,负压创面组创面细菌负荷低于敷料包扎组(P<0.01),创面微循环血流量高于敷料包扎组(P<0.01)。负压创面组创面愈合时间少于敷料包扎组(P<0.01)。结论:负压创面治疗有助于慢性肝硬化并发糖尿病合并糖尿病足的创面愈合。
Objective: To discuss the clinical effect of negative pressure wound therapy on cirrhosis with diabetic and diabetic foot. Methods: Thirty patients with chronic liver cirrhosis complicated with diabetic foot were randomly divided into wound negative pressure treatment group and dressing dressing group. Bacterial load and wound microcirculation blood flow changes were observed in two groups. Results: There was no significant difference in bacterial load between the wound dressing group and the wound dressing group and the wound microcirculation blood flow (P> 0.01). The wound bacterial load of the wounds of negative pressure wound group at 3 days, 6 days and 9 days after wounding were significantly lower Lower than dressing dressing group (P <0.01), wound blood flow was higher than dressing dressing group (P <0.01). The wound healing time of negative pressure wound group was less than dressing dressing group (P <0.01). Conclusion: Negative pressure wound treatment is helpful for wound healing of diabetic patients with chronic liver cirrhosis and diabetic foot.