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本文应用无创性收缩时间间期测定(STI)方法,观察了110例慢性阻塞性肺部疾病(COPD)患者的心脏工作状况。结果提示:COPD患者STI异常较早出现,表现为射血前间期(PEP)延长(P<0.001),左室射血时间(LVET)缩短(P<0.001),PEP/LVET比值增大(P<0.001)。当合并肺心病和伴心衰出现时,PEP/LVET增大更明显(P<0.001),同时还观察到,STI的异常与动脉血气变化和肺功能之间存在一定的相关关系。肺动脉高压,右室搏出和左心灌注减少,左室输出量降低,可能是引起COPD肺心病患者STI异常的主要原因。
In this paper, noninvasive systolic time interval (STI) method was used to observe the working status of heart in 110 patients with chronic obstructive pulmonary disease (COPD). The results suggest that STI abnormalities in COPD patients appeared earlier, with prolonged pre-ejection period (P <0.001), shorter LVET (P <0.001), and increased PEP / LVET ratio P <0.001). PEP / LVET increased more significantly when combined with cor pulmonale and heart failure (P <0.001). There was also a correlation between STI abnormalities and arterial blood gas changes and pulmonary function. Pulmonary hypertension, right ventricular stroke and left ventricular perfusion decreased left ventricular output decreased, may be caused by COPD pulmonary heart disease STI abnormalities in the main reason.