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目的探讨大面积脑梗死、非大面积脑梗死及短暂脑缺血发作(TIA)患者血小板聚集率的差异。方法选取2008年1月至2009年1月急性大面积脑梗死患者24例、非大面积脑梗死50例、TIA患者28例,入院次日行血小板聚集率的检查,对比3组患者血小板聚集率的差异。结果脑梗死两组患者血小板聚集率[(64.3±13.9)%,(62.7±13.9)%]明显高于TIA组的(51.7±15.6)%,P<0.01,而脑梗死两组间差异无统计学意义。结论脑梗死患者血小板聚集率明显高于TIA患者,表明血小板活化可能对于脑梗死的发生发挥重要作用,故脑梗死患者更需加强抗血小板治疗。
Objective To investigate the difference of platelet aggregation in large area cerebral infarction, non-large area cerebral infarction and transient ischemic attack (TIA). Methods From January 2008 to January 2009, 24 patients with acute massive cerebral infarction, 50 patients with non-large-area cerebral infarction, 28 patients with TIA were enrolled in this study. The platelet aggregation rate was examined on the next day after admission. The platelet aggregation rate The difference. Results The platelet aggregation rate in the two groups was significantly higher than that in the TIA group (64.3 ± 13.9% vs 62.7 ± 13.9%, P <0.01), but there was no significant difference between the two groups Significance of learning. Conclusion Platelet aggregation in patients with cerebral infarction was significantly higher than TIA patients, indicating that platelet activation may play an important role in the occurrence of cerebral infarction, so the need for more anti-platelet therapy in patients with cerebral infarction.