新生儿缺血缺氧性脑病(hypoxic ischenic encephalopathy,HIE)是由于各种围生期因素引起的缺氧和脑血流量减少或暂停而导致胎儿和新生儿的脑损伤,易导致新生儿早期死亡及(或)神经系统永久性损害,引起脑性瘫痪,癫痫、语言障碍、听力障碍及共济失调等后遗症。提高HIE的临床疗效在降低新生儿期病死率及减低存活者神经系统后遗症的发生方面,具有非常重要的临床意义。为此,我们对HIE患儿,在药物治疗的基础上,予以高压氧治疗,取得了较好的临床疗效,现报告如下。 Neonatal hypoxic ischenic encephalopathy (HIE) is a brain injury of the fetus and the newborn due to hypoxia and decrease or pause of cerebral blood flow caused by various perinatal factors, leading to early neonatal death And / or permanent damage to the nervous system causing sequelae such as cerebral palsy, epilepsy, speech impairment, hearing loss and ataxia. To improve the clinical efficacy of HIE in reducing mortality in neonates and reduce the occurrence of neurological sequelae in survivors, has a very important clinical significance. To this end, we HIE children, based on the drug treatment, hyperbaric oxygen therapy, and achieved good clinical efficacy, are as follows.