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为探讨急性白血病发生院内感染的易感因素。采用回顾调查方法对162例次院内感染进行分析。结果:急性白血病院内感染率为住院次数的61.6％;感染部位以呼吸道、口腔、皮肤软组织、败血症为主;感染细菌主要为G~-杆菌、真菌;院内感染与化疗、白细胞计数、环境的消毒隔离以及抗生素应用密切相关。结论:为了减少院内感染的发生率和病死率,除选择最佳方案治疗白血病本身外。应对其化疗后的粒细胞缺乏期给予良好的支持治疗,尽快缩短粒细胞缺乏期,提高患者的免疫力;加强白血病病房及患者的消毒隔离措施;合理应用抗生素。
To investigate the predisposing factors of nosocomial infection in acute leukemia. A retrospective survey was used to analyze 162 cases of nosocomial infection. Results: The rate of nosocomial infection in acute leukemia was 61.6% of the number of hospitalizations; respiratory tract, oral cavity, soft tissue and sepsis were the main sites of infection; bacteria were mainly G~-bacilli and fungi; nosocomial infections and chemotherapy, white blood cell counts, environmental disinfection Isolation and antibiotic use are closely related. Conclusion: In order to reduce the incidence of hospital infection and mortality, in addition to selecting the best treatment for leukemia itself. We should provide good supportive treatment for the lack of agranulocytosis after chemotherapy, shorten the agranulocytosis period as quickly as possible, and improve the patient’s immunity; strengthen the disinfection and isolation measures for leukemia wards and patients; and rationally use antibiotics.