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61例糖尿病肾病患者在积极控制血糖的基础上,随机分为对照组30例,予福辛普利(蒙诺)及缬沙坦(代文)口服,观察组31例在缬沙坦(代文)基础上,每日静脉给予黄芪注射液40ml滴注。结果:两组病例用药后收缩压、舒张压较用药前降低,有显著性差异(P<0.01),但是,观察组的收缩压较对照组高,有明显差异(P<0.001);观察组的舒张压也较高,但是无明显差异(P=0.05)。观察组与对照组的治疗后UEAR均有显著性减少(P<0.01),但观察组优于对照组(P<0.05)。结论:黄芪注射液联合缬沙坦有相互协同的作用,疗效优于缬沙坦福辛普利组,同时咳嗽等副作用更少。
61 patients with diabetic nephropathy on the basis of active control of blood glucose, were randomly divided into control group of 30 cases, to fosinopril (Monel) and valsartan (on behalf of) orally, the observation group of 31 patients in the valsartan (on behalf of) Based on the daily intravenous administration of Astragalus injection 40ml infusion. Results: The systolic blood pressure and diastolic blood pressure of the two groups were significantly lower than those before treatment (P <0.01), but the systolic blood pressure of the observation group was higher than that of the control group (P <0.001) Diastolic blood pressure was also higher, but no significant difference (P = 0.05). The UEAR in the observation group and the control group were significantly decreased (P <0.01), but the observation group was better than the control group (P <0.05). Conclusion: Astragalus injection combined with valsartan has a synergistic effect, which is superior to valsartan and fosinopril, and has fewer side effects such as cough.